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Elyse Singer, M.D.

Email Address:
esinger@ucla.edu

Mailing Address:
Practice Location
300 UCLA Medical Plaza B-200
Los Angeles, CA 90095
UNITED STATES

Neurology
11645 Wilshire Blvd, Ste 770
Los Angeles, CA 90025
UNITED STATES




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Department / Division Affiliations
Professor, Neurology
Member, Brain Research Institute

Publications:

Lamers Susanna L, Fogel Gary B, Singer Elyse J, Salemi Marco, Nolan David J, Huysentruyt Leanne C, McGrath Michael S HIV-1 Nef in macrophage-mediated disease pathogenesis. International reviews of immunology. 2012; 31(6): 432-50.
Gelman Benjamin B, Lisinicchia Joshua G, Morgello Susan, Masliah Eliezer, Commins Deborah, Achim Cristian L, Fox Howard S, Kolson Dennis L, Grant Igor, Singer Elyse, Yiannoutsos Constantin T, Sherman Seth, Gensler Gary, Moore David J, Chen Tiansheng, Soukup Vicki M Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort. Journal of acquired immune deficiency syndromes (1999). 2012; .
Soontornniyomkij Virawudh, Moore David J, Gouaux Ben, Soontornniyomkij Benchawanna, Tatro Erick T, Umlauf Anya, Masliah Eliezer, Levine Andrew J, Singer Elyse J, Vinters Harry V, Gelman Benjamin B, Morgello Susan, Cherner Mariana, Grant Igor, Achim Cristian L Cerebral ?-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ?4 carriers. AIDS (London, England). 2012; 26(18): 2327-35.
Levine Andrew J, Service Susan, Miller Eric N, Reynolds Sandra M, Singer Elyse J, Shapshak Paul, Martin Eileen M, Sacktor Ned, Becker James T, Jacobson Lisa P, Thompson Paul, Freimer Nelson Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2012; 159B(6): 669-83.
Kamat Anupa, Lyons Jennifer L, Misra Vikas, Uno Hajime, Morgello Susan, Singer Elyse J, Gabuzda Dana Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection. Journal of acquired immune deficiency syndromes (1999). 2012; 60(3): 234-43.
Levine Andrew J, Sinsheimer Janet S, Bilder Robert, Shapshak Paul, Singer Elyse J Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults. Journal of clinical and experimental neuropsychology. 2012; 34(1): 78-91.
Dye Richelin V, Miller Karen J, Singer Elyse J, Levine Andrew J Hormone replacement therapy and risk for neurodegenerative diseases. International journal of Alzheimer's disease. 2012; 2012(4): 258454.
Robinson-Papp Jessica, Gelman Benjamin B, Grant Igor, Singer Elyse, Gensler Gary, Morgello Susan, Morgello Susan Substance abuse increases the risk of neuropathy in an HIV-infected cohort. Muscle & nerve. 2012; 45(4): 471-6.
Gelman Benjamin B, Chen Tiansheng, Lisinicchia Joshua G, Soukup Vicki M, Carmical J Russ, Starkey Jonathan M, Masliah Eliezer, Commins Deborah L, Brandt Dianne, Grant Igor, Singer Elyse J, Levine Andrew J, Miller Jeremy, Winkler Jessica M, Fox Howard S, Luxon Bruce A, Morgello Susan, Morgello Susan The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. PloS one. 2012; 7(9): e46178.
Sowmya Gopichandran, Shamini Gunasagaran, Anita Sathyanarayanan, Sakharkar Meena, Mathura Venkat, Rodriguez Hector, Levine Andrew J, Singer Elyse, Commins Deborah, Somboonwit Charurut, Sinnott John T, Sidhu Harcharan S, Rajaseger Ganapathy, Pushparaj Peter Natesan, Kangueane Pandajarasamme, Shapshak Paul HIV-1 envelope accessible surface and polarity: clade, blood, and brain. Bioinformation. 2011; 6(2): 48-56.
Lyons Jennifer L, Uno Hajime, Ancuta Petronela, Kamat Anupa, Moore David J, Singer Elyse J, Morgello Susan, Gabuzda Dana Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. Journal of acquired immune deficiency syndromes (1999). 2011; 57(5): 371-9.
Tate David F, Sampat Mehul, Harezlak Jaroslaw, Fiecas Mark, Hogan Joseph, Dewey Jeffrey, McCaffrey Daniel, Branson Daniel, Russell Troy, Conley Jared, Taylor Michael, Schifitto Giovanni, Schifitto Giavoni, Zhong J, Daar Eric S, Alger Jeffrey, Brown Mark, Singer Elyse, Campbell T, McMahon D, Tso Y, Matesan Janetta, Letendre Scott, Paulose S, Gaugh Michelle, Tripoli C, Yiannoutsos Constantine, Bigler Erin D, Cohen Ronald A, Guttmann Charles R G, Navia Bradford, Navia Bradford Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies. Journal of neurovirology. 2011; 17(4): 368-79.
Harezlak Jarek, Buchthal Steven, Taylor Michael, Schifitto Giovanni, Zhong Jianhui, Daar Eric, Alger Jeffrey, Singer Elyse, Campbell Thomas, Yiannoutsos Constantin, Cohen Ronald, Navia Bradford, Navia Bradford Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. AIDS (London, England). 2011; 25(5): 625-33.
Thames April D, Becker Brian W, Marcotte Thomas D, Hines Lindsay J, Foley Jessica M, Ramezani Amir, Singer Elyse J, Castellon Steven A, Heaton Robert K, Hinkin Charles H Depression, cognition, and self-appraisal of functional abilities in HIV: an examination of subjective appraisal versus objective performance. The Clinical neuropsychologist. 2011; 25(2): 224-43.
Thames April D, Kim Michelle S, Becker Brian W, Foley Jessica M, Hines Lindsay J, Singer Elyse J, Heaton Robert K, Castellon Steven A, Hinkin Charles H Medication and finance management among HIV-infected adults: the impact of age and cognition. Journal of clinical and experimental neuropsychology. 2011; 33(2): 200-9.
Shapshak Paul, Kangueane Pandjassarame, Fujimura Robert K, Commins Deborah, Chiappelli Francesco, Singer Elyse, Levine Andrew J, Minagar Alireza, Novembre Francis J, Somboonwit Charurut, Nath Avindra, Sinnott John T Editorial neuroAIDS review. AIDS (London, England). 2011; 25(2): 123-41.
Shapshak Paul, Somboonwit Charurut, Sinnott John, Commins Deborah, Singer Elyse, Levine Andrew Gene-chromosome locations of neuropsychiatric diseases. Bioinformation. 2011; 7(7): 366-8.
Shapshak Paul, Duncan Robert, Kangueane Pandajarasamme, Somboonwit Charurut, Sinnott John, Commins Deborah, Singer Elyse, Levine Andrew HIV associated dementia and HIV encephalitis II: Genes on chromosome 22 expressed in individually microdissected Globus pallidus neurons (Preliminary analysis). Bioinformation. 2011; 6(5): 183-6.
Cohen Ronald A, Harezlak Jaroslaw, Gongvatana Assawin, Buchthal Steven, Schifitto Giovanni, Clark Uraina, Paul Robert, Taylor Michael, Thompson Paul, Tate David, Alger Jeffery, Brown Mark, Zhong Jianhui, Campbell Thomas, Singer Elyse, Daar Eric, McMahon Deborah, Tso Yuen, Yiannoutsos Constantin T, Navia Bradford, Navia Bradford Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes. Journal of neurovirology. 2010; 16(6): 435-44.
Cohen Ronald A, Harezlak Jaroslaw, Schifitto Giovanni, Hana George, Clark Uraina, Gongvatana Assawin, Paul Robert, Taylor Michael, Thompson Paul, Alger Jeffery, Brown Mark, Zhong Jianhui, Campbell Thomas, Singer Elyse, Daar Eric, McMahon Deborah, Tso Yuen, Yiannoutsos Constantin T, Navia Bradford Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era. Journal of neurovirology. 2010; 16(1): 25-32.
Zhao Yu, Navia Bradford A, Marra Christina M, Singer Elyse J, Chang Linda, Berger Joseph, Ellis Ronald J, Kolson Dennis L, Simpson David, Miller Eric N, Lipton Stuart A, Evans Scott R, Schifitto Giovanni, Schifitto Giovanni Memantine for AIDS dementia complex: open-label report of ACTG 301. HIV clinical trials. 2010; 11(1): 59-67.
Singer Elyse J, Valdes-Sueiras Miguel, Commins Deborah, Levine Andrew Neurologic presentations of AIDS. Neurologic clinics. 2010; 28(1): 253-75.
Levine Andrew J, Singer Elyse J, Sinsheimer Janet S, Hinkin Charles H, Papp Jeanette, Dandekar Sugandha, Giovanelli Allison, Shapshak Paul CCL3 genotype and current depression increase risk of HIV-associated dementia. Neurobehavioral HIV medicine. 2009; 1(1): 1-7.
Kumar Adarsh M, Fernandez J B, Singer Elyse J, Commins Deborah, Waldrop-Valverde Drenna, Ownby Raymond L, Kumar Mahendra Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains. Journal of neurovirology. 2009; 15(3): 257-74.
Micheletti Robert G, Fishbein Gregory A, Fishbein Michael C, Singer Elyse J, Weiss Robert E, Jeffries Robin A, Currier Judith S Coronary atherosclerotic lesions in human immunodeficiency virus-infected patients: a histopathologic study. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2009; 18(1): 28-36.
Giunta Brian, Hou Houyan, Zhu Yuyan, Rrapo Elona, Tian Jun, Takashi Mori, Commins Deborah, Singer Elyse, He Johnny, Fernandez Francisco, Tan Jun HIV-1 Tat contributes to Alzheimer's disease-like pathology in PSAPP mice. International journal of clinical and experimental pathology. 2009; 2(5): 433-43.
Shapshak Paul, Somboonwit Charurut, Drumright Lydia N, Frost Simon D W, Commins Deborah, Tellinghuisen Timothy L, Scott William K, Duncan Robert, McCoy Clyde, Page J Bryan, Giunta Brian, Fernandez Francisco, Singer Elyse, Levine Andrew, Minagar Alireza, Oluwadara Oluwadayo, Kotila Taiwo, Chiappelli Francesco, Sinnott John T Molecular and contextual markers of hepatitis C virus and drug abuse. Molecular diagnosis & therapy. 2009; 13(3): 153-79.
Levine Andrew J, Singer Elyse J, Shapshak Paul The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders. AIDS and behavior. 2009; 13(1): 118-32.
Levine Andrew J, Hinkin Charles H, Ando Kazuhiro, Santangelo Gianni, Martinez Mariana, Valdes-Sueiras Miguel, Saxton Ernestina H, Mathisen Glen, Commins Deborah L, Moe Ardis, Farthing Charles, Singer Elyse J An exploratory study of long-term neurocognitive outcomes following recovery from opportunistic brain infections in HIV+ adults. Journal of clinical and experimental neuropsychology. 2008; 30(7): 836-43.
Fishbein Gregory A, Micheletti Robert G, Currier Judith S, Singer Elyse, Fishbein Michael C Atherosclerotic oxalosis in coronary arteries. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2008; 17(2): 117-23.
Micheletti Robert G, Fishbein Gregory A, Currier Judith S, Singer Elyse J, Fishbein Michael C Calcification of the internal elastic lamina of coronary arteries. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2008; 21(8): 1019-28.
Fiala Milan, Singer Elyse J, Commins Deborah, Mirzapoiazova Tamara, Verin Alexander, Espinosa Araceli, Ugen Kenneth, Bernas Michael, Witte Marlys, Weinand Martin, Lossinsky Albert S HIV-1 Antigens in Neurons of Cocaine-Abusing Patients. The open virology journal. 2008; 2(1): 24-31.
Ancuta Petronela, Kamat Anupa, Kunstman Kevin J, Kim Eun-Young, Autissier Patrick, Wurcel Alysse, Zaman Tauheed, Stone David, Mefford Megan, Morgello Susan, Singer Elyse J, Wolinsky Steven M, Gabuzda Dana Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PloS one. 2008; 3(6): e2516.
Chiappelli Francesco, Shapshak Paul, Commins Deborah, Singer Elyse, Minagar Alireza, Oluwadara Oluwadayo, Prolo Paolo, Pellionisz Andras J Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications. Bioinformation. 2008; 3(1): 47-52.
Shapshak Paul, Chiappelli Francesco, Commins Deborah, Singer Elyse, Levine Andrew J, Somboonwit Charurut, Minagar Alireza, Pellionisz Andras J Molecular epigenetics, chromatin, and NeuroAIDS/HIV: translational implications. Bioinformation. 2008; 3(1): 53-7.
Minagar Alireza, Commins Deborah, Alexander J Steven, Hoque Romy, Chiappelli Francesco, Singer Elyse J, Nikbin Behrooz, Shapshak Paul NeuroAIDS: characteristics and diagnosis of the neurological complications of AIDS. Molecular diagnosis & therapy. 2008; 12(1): 25-43.
Hinkin Charles H, Castellon Steven A, Levine Andrew J, Barclay Terry R, Singer Elyse J Neurocognition in individuals co-infected with HIV and hepatitis C. Journal of addictive diseases. 2008; 27(2): 11-7.
Schifitto Giovanni, Navia Bradford A, Yiannoutsos Constantin T, Marra Christina M, Chang Linda, Ernst Thomas, Jarvik Jeffrey G, Miller Eric N, Singer Elyse J, Ellis Ronald J, Kolson Dennis L, Simpson David, Nath Avindra, Berger Joseph, Shriver Sharon L, Millar Linda L, Colquhoun Dodi, Lenkinski Robert, Gonzalez R Gilberto, Lipton Stuart A, Lipton Stuart A, Lipton Stuart A, Lipton Stuart A Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. AIDS (London, England). 2007; 21(14): 1877-86.
Paul Robert H, Yiannoutsos Constantin T, Miller Eric N, Chang Linda, Marra Christina M, Schifitto Giovanni, Ernst Thomas, Singer Elyse, Richards Todd, Jarvik G Jeffrey, Price Richard, Meyerhoff Dieter J, Kolson Dennis, Ellis Ronald J, Gonzalez Gilberto, Lenkinski Robert E, Cohen Ronald A, Navia Bradford A Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity. The Journal of neuropsychiatry and clinical neurosciences. 2007; 19(3): 283-92.
Rohit Mona, Levine Andrew, Hinkin Charles, Abramyan Shogik, Saxton Ernestine, Valdes-Sueiras Miguel, Singer Elyse Education correction using years in school or reading grade-level equivalent? Comparing the accuracy of two methods in diagnosing HIV-associated neurocognitive impairment. Journal of the International Neuropsychological Society : JINS. 2007; 13(3): 462-70.
Schifitto Giovanni, Yiannoutsos Constantin T, Simpson David M, Marra Christina M, Singer Elyse J, Kolson Dennis L, Nath Avindra, Berger Joseph R, Navia Bradford, Navia Bradford A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy. Journal of neurovirology. 2006; 12(4): 328-31.
Fiala Milan, Eshleman Amy J, Cashman John, Lin Justin, Lossinsky Albert S, Suarez Vannina, Yang Wendy, Zhang Jun, Popik Waldemar, Singer Elyse, Chiappelli Francesco, Carro Eva, Weinand Martin, Witte Marlys, Arthos James Cocaine increases human immunodeficiency virus type 1 neuroinvasion through remodeling brain microvascular endothelial cells. Journal of neurovirology. 2005; 11(3): 281-91.
Woods Steven Paul, Rippeth Julie D, Frol Alan B, Levy Joel K, Ryan Elizabeth, Soukup Vicki M, Hinkin Charles H, Lazzaretto Deborah, Cherner Mariana, Marcotte Thomas D, Gelman Benjamin B, Morgello Susan, Singer Elyse J, Grant Igor, Heaton Robert K Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV. Journal of clinical and experimental neuropsychology. 2004; 26(6): 759-78.
Singer Elyse J Patient page. A new clue in the mystery of neuro-AIDS. Neurology. 2003; 60(12): E12-3.
Singer Elyse J, Aronow H Aaron, Lee Shing-Yi, Hinkin Charles H, Lazarus Tadd Stability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive). Journal of clinical microbiology. 2002; 40(10): 3863-4.