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Ligia Toro, Ph.D.

Work Email Address:
ltoro@mednet.ucla.edu

Laboratory Address:
Laboratory
CHS BH-530

UNITED STATES

Work Address:
Office
CHS BH-528

UNITED STATES

Office Phone Number:
310 794 7809
310-794-7810



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Department / Division Affiliations
Professor, Anesthesiology, Molecular & Medical Pharmacology
Member, ACCESS Program: Dept. of Molecular & Medical Pharmacology, Molecular Medicine, Brain Research Institute
Faculty, Cardiovascular Research Laboratory

Bio:

Ligia Toro is a physiologist and biophysicist who joined UCLA School of Medicine in 1994 as member of the department of Anesthesiology. She became a full professor in 2000. Dr. Toro was trained in Mexico where she received a B.S. degree in Chemistry from Universidad IberoAmericana, a M.S. degree in Biochemistry from Universidad Autonoma Metropolitana-Iztapalapa and a Ph.D. in Physiology and Biophysics from Centro de Investigacion y Estudios Avanzados del IPN. In 1987, she moved to Baylor College of Medicine in Houston, TX for postdoctoral training. In 1990, she was promoted to Assistant Professor in the same institution. Her postdoctoral work was on ion channel biophysics and metabolic regulation. At present, Dr. Toro is Professor of the Department of Anesthesiology and the Department of Molecular and Medical Pharmacology, and is member of the Brain Research Institute and of the Cardiovascular Research Laboratory. She participates on several training grants and cardiovascular research programs at UCLA. She has served as regular member of NIH study sections, in the council and executive board of the Biophysical Society, and has chaired the International Relations Committee of the Biophysical Society and the US National Committee for the International Union of Pure and Applied Biophysics. In 2001, she became Fellow of the American Heart Association and in 2009, she was designated Dorothy and Leonard Straus Scholar at UCLA.

Publications:

Singh Harpreet, Lu Rong, Rodriguez Pedro Felipe Gardeazabal, Wu Yong, Bopassa Jean Chrisostome, Stefani Enrico, Toro Ligia Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy. Mitochondrion. 2012; 12 : 230236.
Danesh Shahab M, Kundu Pallob, Lu Rong, Stefani Enrico, Toro Ligia Distinct transcriptional regulation of human large conductance voltage- and calcium-activated K+ channel gene (hSlo1) by activated estrogen receptor alpha and c-Src tyrosine kinase. The Journal of Biological Chemistry. 2011; 286(36): 31064-71.
Alioua Abderrahmane, Li Min, Wu Yong, Stefani Enrico, Toro Ligia Unconventional myristoylation of large-conductance Ca2+-activated K+ channel (Slo1) via serine/threonine residues regulates channel surface expression. Proceedings of the National Academy of Sciences of the United States of America. 2011; 108(26): 10744-9.
Li Min, Tanaka Yoshio, Alioua Abderrahmane, Wu Yong, Lu Rong, Kundu Pallob, Sanchez-Pastor Enrique, Marijic Jure, Stefani Enrico, Toro Ligia Thromboxane A2 receptor and MaxiK-channel intimate interaction supports channel trans-inhibition independent of G-protein activation. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(44): 19096-101.
Bopassa Jean Chrisostome, Eghbali Mansoureh, Toro Ligia, Stefani Enrico A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 2010; 298(1): H16-23.