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Gene Block, Ph.D.

Work Email Address:
chancellor@conet.ucla.edu

Mailing Address:
capmus mail code: 14501

UNITED STATES

10570 SUNSET BLVD
Los Angeles, CA 90077
UNITED STATES

Work Address:
CHS 2147

UNITED STATES

UCLA Chan Ofc
2147 Murphy Hall
BOX 951405
Los Angeles, CA 90095
UNITED STATES

Work Phone Number:
310-825-2151



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Department / Division Affiliations
Distinguished Professor, Integrative Biology and Physiology, Psychiatry and Biobehavioral Sciences
Chancellor, UCLA
Member, ACCESS Program: Dept. of Molecular, Cell & Integrative Physiology, Institutional Steering Committee, CTSI
Faculty, Molecular, Cellular, and Integrative Physiology IDP

Publications:

Kudo Takashi, Tahara Yu, Gamble Karen L, McMahon Douglas G, Block Gene D, Colwell Christopher S Vasoactive intestinal peptide produces long-lasting changes in neural activity in the suprachiasmatic nucleus. Journal of neurophysiology. 2013; .
Sellix Michael T, Evans Jennifer A, Leise Tanya L, Castanon-Cervantes Oscar, Hill DiJon D, DeLisser Patrick, Block Gene D, Menaker Michael, Davidson Alec J Aging differentially affects the re-entrainment response of central and peripheral circadian oscillators. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012; 32(46): 16193-202.
Nakamura Takahiro J, Nakamura Wataru, Yamazaki Shin, Kudo Takashi, Cutler Tamara, Colwell Christopher S, Block Gene D Age-related decline in circadian output. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011; 31(28): 10201-5.
Gale John E, Cox Heather I, Qian Jingyi, Block Gene D, Colwell Christopher S, Matveyenko Aleksey V Disruption of circadian rhythms accelerates development of diabetes through pancreatic beta-cell loss and dysfunction. Journal of biological rhythms. 2011; 26(5): 423-33.
Loh Dawn H, Dragich Joanna M, Kudo Takashi, Schroeder Analyne M, Nakamura Takahiro J, Waschek James A, Block Gene D, Colwell Christopher S Effects of vasoactive intestinal peptide genotype on circadian gene expression in the suprachiasmatic nucleus and peripheral organs. Journal of biological rhythms. 2011; 26(3): 200-9.
Lundkvist Gabriella B S, Sellix Michael T, Nygård Mikael, Davis Erin, Straume Marty, Kristensson Krister, Block Gene D Clock gene expression during chronic inflammation induced by infection with Trypanosoma brucei brucei in rats. Journal of biological rhythms. 2010; 25(2): 92-102.
Nakamura Takahiro J, Sellix Michael T, Kudo Takashi, Nakao Nobuhiro, Yoshimura Takashi, Ebihara Shizufumi, Colwell Christopher S, Block Gene D Influence of the estrous cycle on clock gene expression in reproductive tissues: effects of fluctuating ovarian steroid hormone levels. Steroids. 2010; 75(3): 203-12.
Yamazaki Shin, Yoshikawa Tomoko, Biscoe Elizabeth W, Numano Rika, Gallaspy Lauren M, Soulsby Stacy, Papadimas Evagelia, Pezuk Pinar, Doyle Susan E, Tei Hajime, Sakaki Yoshiyuki, Block Gene D, Menaker Michael Ontogeny of circadian organization in the rat. Journal of biological rhythms. 2009; 24(1): 55-63.
Nakamura Takahiro J, Sellix Michael T, Menaker Michael, Block Gene D Estrogen directly modulates circadian rhythms of PER2 expression in the uterus. American journal of physiology. Endocrinology and metabolism. 2008; 295(5): E1025-31.
Nakamura Wataru, Yamazaki Shin, Nakamura Takahiro J, Shirakawa Tetsuo, Block Gene D, Takumi Toru In vivo monitoring of circadian timing in freely moving mice. Current biology : CB. 2008; 18(5): 381-5.
Kwak Yongho, Lundkvist Gabriella B, Brask Johan, Davidson Alec, Menaker Michael, Kristensson Krister, Block Gene D Interferon-gamma alters electrical activity and clock gene expression in suprachiasmatic nucleus neurons. Journal of biological rhythms. 2008; 23(2): 150-9.
Davidson Alec J, Yamazaki Shin, Arble Deanna M, Menaker Michael, Block Gene D Resetting of central and peripheral circadian oscillators in aged rats. Neurobiology of aging. 2008; 29(3): 471-7.
VanderLeest Henk Tjebbe, Houben Thijs, Michel Stephan, Deboer Tom, Albus Henk, Vansteensel Mariska J, Block Gene D, Meijer Johanna H Seasonal encoding by the circadian pacemaker of the SCN. Current biology : CB. 2007; 17(5): 468-73.
Davidson Alec J, Straume Martin, Block Gene D, Menaker Michael Daily timed meals dissociate circadian rhythms in hepatoma and healthy host liver. International journal of cancer. Journal international du cancer. 2006; 118(7): 1623-7.
Albus Henk, Vansteensel Mariska J, Michel Stephan, Block Gene D, Meijer Johanna H A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clock. Current biology : CB. 2005; 15(10): 886-93.
Lundkvist Gabriella B, Kwak Yongho, Davis Erin K, Tei Hajime, Block Gene D A calcium flux is required for circadian rhythm generation in mammalian pacemaker neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005; 25(33): 7682-6.
Nakamura Wataru, Yamazaki Shin, Takasu Nana N, Mishima Kazuo, Block Gene D Differential response of Period 1 expression within the suprachiasmatic nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005; 25(23): 5481-7.
Block Gene Keep time, stay healthy. Science of aging knowledge environment : SAGE KE. 2005; 2005(19): pe13.
Lundkvist Gabriella B, Block Gene D Role of neuronal membrane events in circadian rhythm generation. Methods in enzymology. 2005; 393(19): 623-42.
Aton Sara J, Block Gene D, Tei Hajime, Yamazaki Shin, Herzog Erik D Plasticity of circadian behavior and the suprachiasmatic nucleus following exposure to non-24-hour light cycles. Journal of biological rhythms. 2004; 19(3): 198-207.
Vansteensel Mariska J, Yamazaki Shin, Albus Henk, Deboer Tom, Block Gene D, Meijer Johanna H Dissociation between circadian Per1 and neuronal and behavioral rhythms following a shifted environmental cycle. Current biology : CB. 2003; 13(17): 1538-42.
Davidson Alec J, Aujard Fabienne, London Brian, Menaker Michael, Block Gene D Thermochron ibuttons: an inexpensive method for long-term recording of core body temperature in untethered animals. Journal of biological rhythms. 2003; 18(5): 430-2.
Constance Cara M, Green Carla B, Tei Hajime, Block Gene D Bulla gouldiana period exhibits unique regulation at the mRNA and protein levels. Journal of biological rhythms. 2002; 17(5): 413-27.
Abe Michikazu, Herzog Erik D, Yamazaki Shin, Straume Marty, Tei Hajime, Sakaki Yoshiyuki, Menaker Michael, Block Gene D Circadian rhythms in isolated brain regions. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002; 22(1): 350-6.
Yamazaki Shin, Straume Marty, Tei Hajime, Sakaki Yoshiyuki, Menaker Michael, Block Gene D Effects of aging on central and peripheral mammalian clocks. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99(16): 10801-6.
Wilsbacher Lisa D, Yamazaki Shin, Herzog Erik D, Song Eun-Joo, Radcliffe Laurel A, Abe Michikazu, Block Gene, Spitznagel Edward, Menaker Michael, Takahashi Joseph S Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice invivo. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99(1): 489-94.