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Paul Macey, Ph.D.

Work Email Address:

Mailing Address:
700 Tiverton Avenue
Los Angeles, CA 90095

Fax Number:
(310) 825-2224
Work Phone Number:
(310) 206-1679

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Department / Division Affiliations
Assistant Professor, School of Nursing
Member, Brain Research Institute

Research Interest:

Central control of sleep and breathing, and changes in CNS with sleep-disordered breathing

I investigate patients with sleep-disordered breathing, including obstructive sleep apnea (OSA), using neuroimaging to show how the brain is impacted in the condition. I am especially interested in how brain changes are influenced by factors other than sleep-disordered breathing, including depression. My earlier work showed that both structure and function is affected in OSA, and I have recently found that depression contributes to the deficits we see. I aim to combine a variety of MRI data (diffusion tensor imaging, T2 relaxation time, high-resolution structural imaging, spectroscopy, and functional imaging) and narrow down the nature of the brain pathology. Future research questions are whether the brain changes precede or are a consequence of OSA and depression, whether the combination of OSA and depression has a cumulative detrimental impact on the brain relative to each condition alone, and exactly what areas of the brain are affected, relative to a large population sample.