Site Search



Stephanie White, Ph.D.

Email Address:
sawhite@ucla.edu

Work Address:
Laboratory
610 Charles Young Drive, East
Los Angeles, CA 90095
UNITED STATES

Office
610 Charles Young Drive, East
Los Angeles, CA 90095
UNITED STATES

Lab Number:
(310) 267-4017
Office Phone Number:
(310) 794-1888



Login to the Faculty Database

Department / Division Affiliations
Professor, Integrative Biology and Physiology, Tennenbaum Center for the Biology of Creativity
Member, ACCESS Program: Dept. of Molecular, Cell & Integrative Physiology, Access Molecular, Cellular and Integrative Physiology Home Area, Access Neuroscience Home Area, Brain Research Institute, Neuroscience IDP
Faculty, Molecular, Cellular, and Integrative Physiology IDP

Bio:

Social influences on learning and memory How do social interactions influence the brain? Our laboratory is interested in how social behaviors affect neuronal plasticity at sites responsible for learning in an Australian songbird, the zebra finch. We study song learning behavior that is essential for reproductive opportunity and is mediated by known neural circuitry. In zebra finches, both the learned behavior and its underlying neural structures are sexually dimorphic, and plasticity is greatest during critical developmental phases. Within a comparative framework, we use behavioral, electrophysiological, and molecular techniques to investigate how social interactions shape gene expression patterns, how these changes modulate neural circuit properties and ultimately, how this constellation of changes sculpts behavior.

Publications:

White, SA FoxP2 and vocalisation. 2013; .
*Hilliard AT, *Miller JE, Fraley ER, Horvath S, White SA Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning. Neuron 2012; 73: 537-552.
Hilliard AT, Miller JE, Horvath S & White SA Distinct neurogenomic states in basal ganglia subregions relate differently to singing behavior in songbirds. PLoS Computational Biology 2012; 8: e1002773.
Panaitof SC, Abrahams BS, Dong H, Geschwind DH & White SA Language-related Cntnap2 is differentially expressed in sexually dimorphic nuclei essential for vocal learning in songbirds. Journal of Comparative Neurology 2010; .
Teramitsu I, Poopatanapong A, Torrisi S & White SA Striatal FoxP2 is actively regulated during songbird sensorimotor learning. PLoS ONE. 2010; 5(1): e8548.
Miller JE, Hilliard AT & White SA Song practice promotes acute vocal variability during sensorimotor learning. PLoS ONE. 2010; 5(1): e8592.
White, SA Genes and vocal learning. Brain and Language 2010; 115: 21-28.
Download
Hilliard AT & White SA Evolutionary Precursors of Syntax. Biological Foundations and Origin of Syntax, edited by Derek Bickerton and Eörs Szathmáry; Strüngmann Forum Reports 2009; 3: 161-182.
Számadö S, Bishop D, d?Errico, F, Fischer J, Hurford J, Okanoya K, Szathmáry E & White SA What are the possible biological and genetic foundations for syntactic phenomena?. Biological Foundations and Origin of Syntax, edited by Derek Bickerton and Eörs Szathmáry; Strüngmann Forum Reports 2009; 3: 207-236.
Spence RD, Zhen Y, White S, Schlinger BA, Day LB Recovery of motor and cognitive function after cerebellar lesions in a songbird: role of estrogens. The European Journal of Neuroscience. 2009; 29(6): 1225-34.
Download
Miller Julie E, Spiteri Elizabeth, Condro Michael C, Dosumu-Johnson Ryan T, Geschwind Daniel H, White Stephanie A Birdsong decreases protein levels of FoxP2, a molecule required for human speech. Journal of Neurophysiology. 2008; 100(4): 2015-25.
Teramitsu Ikuko, White Stephanie A Motor learning: the FoxP2 puzzle piece. Current Biology. 2008; 18(8): R335-7.
JE Miller & SA White The sleeping bird gets the song. Journal of Neurophysiology 2007; 98: 3-4.
Download
Wada K, Howard J, McDonnell P, Lints T, Rivas MV, Whitney O, Horita H, Patterson M, White SA,Scharff C, Haesler S, Zhao S, Sakaguchi H, Hagiwara M, Shiraki T, Hirozane-Kishikawa T, Skene P, Hayashizaki Y, Carninci P& Jarvis ED A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes. PNAS. 2006; 103: 15212-15217.
Download
Teramitsu I & White SA FoxP2 regulation during undirected singing in adult songbirds. Journal of Neuroscience. 2006; 26: 7390-7394.
Download
White SA, Fisher SE, Geschwind DH, Scharff C, Holy TE Singing mice, songbirds and more: models for FOXP2 function and dysfunction in human speech and language. Journal of Neuroscience. 2006; 26: 10376-10379.
Download
Poopatanapong A, Teramitsu I, Byun JS,Vician LJ, Herschman HR, White SA Singing, but not seizure, induces Synaptotagmin IV in zebra finch song nuclei. Journal of Neurobiology. 2006; 66: 1613-1629.
Download
Nilson, PC Teramitsu, I White, SA Caudal thoracic air sac cannulation in zebra finches for isoflurane anesthesia. Journal of Neuroscience Methods. 2005; 143: 107-15.
Download
The Avian Brain Nomenclature Consortium Avian brains and a paradigm shift in understanding vertebrate brain evolution. Nature Reviews Neuroscience 2005; 6: 151-159.
Download
Reiner A, Perkel D, Bruce L, Butler A, Csillag A, Kuenzel W, Medina L, Paxinos G, Powers A, Shimisu T, Striedter G, Wild M, Ball G, Durand S, Gunturkun O, Lee D, Mello C, White SA, Hough T, Kubikova L, Smulders T, Wada K, Dugas-Ford J, Husband S, Yamamoto K, Yu J, Siang C, Jarvis ED Revised nomenclature for avian telencephalon and some related brain nuclei. Journal of Comparative Neurology. 2004; 473: 377-414.
Teramitsu, I Kudo, LC London, SE Geschwind, DH White, SA Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction. The Journal of Neuroscience. 2004; 24(13): 3152-63.
Scharff, C White, SA Genetic components of vocal learning. Annals of the New York Academy of Sciences. 2004; 1016: 325-47.
White, SA Nguyen, T Fernald, RD Social regulation of gonadotropin-releasing hormone. The Journal of Experimental Biology. 2002; 205: 2567-81.
White SA Learning to communicate. Current Opinion in Neurobiology. 2001; 11: 510-520.
Livingston*FL, White*SA, & Mooney R Slow NMDA-PSCs at synapses critical for song development are not required for song learning in zebra finches. Nature Neuroscience. 2000; 3: 482-488.
White SA & Mooney R Can an old bird change his tune?. Current Biology. 1999; 9: R688-690.
Fernald RD & White SA Social control of brains: from behavior to genes. The Cognitive Neurosciences 1999; 2nd edition: 1193-1208.
White, SA Livingston, FS Mooney, R Androgens modulate NMDA receptor-mediated EPSCs in the zebra finch song system. Journal of Neurophysiology. 1999; 82(5): 2221-34.
Spiro, JE White, SA Neuroethology: a meeting of brain and behavior. Neuron. 1998; 21(5): 981-9.
White, SA Fernald, RD Changing through doing: behavioral influences on the brain. Recent progress in hormone research. 1997; 52: 455-73; discussion 473-4.
Fox* HE, White* SA, Kau MHF & Fernald RD Stress and dominance in a social fish. Journal of Neuroscience. 1997; 17: 6463-6469.
White, SA Kasten, TL Bond, CT Adelman, JP Fernald, RD Three gonadotropin-releasing hormone genes in one organism suggest novel roles for an ancient peptide. Proceedings of the National Academy of Sciences of the United States of America. 1995; 92(18): 8363-7.
White SA & Fernald RD Gonadotropin-releasing hormone-containing neurons change size with reproductive state in female Haplochromis burtoni. Journal of Neuroscience 1993; 13: 434-441.
White Stephanie A, Fisher Simon E, Geschwind Daniel H, Scharff Constance, Holy Timothy E Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006; 26(41): 10376-9.
Miller Julie E, Hilliard Austin T, White Stephanie A Song practice promotes acute vocal variability at a key stage of sensorimotor learning. PloS one. 2010; 5(1): e8592.
White Stephanie A Genes and vocal learning. Brain and language. 2010; 115(1): 21-8.
Teramitsu Ikuko, Poopatanapong Amy, Torrisi Salvatore, White Stephanie A Striatal FoxP2 is actively regulated during songbird sensorimotor learning. PloS one. 2010; 5(1): e8548.
Hilliard Austin T, Miller Julie E, Fraley Elizabeth R, Horvath Steve, White Stephanie A Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning. Neuron. 2012; 73(3): 537-52.
Nilson Paige Crystal, Teramitsu Ikuko, White Stephanie Ann Caudal thoracic air sac cannulation in zebra finches for isoflurane anesthesia. Journal of neuroscience methods. 2005; 143(2): 107-15.
Teramitsu Ikuko, White Stephanie A FoxP2 regulation during undirected singing in adult songbirds. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006; 26(28): 7390-4.
Hilliard Austin T, Miller Julie E, Horvath Steve, White Stephanie A Distinct neurogenomic states in basal ganglia subregions relate differently to singing behavior in songbirds. PLoS computational biology. 2012; 8(11): e1002773.
Teramitsu Ikuko, Kudo Lili C, London Sarah E, Geschwind Daniel H, White Stephanie A Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004; 24(13): 3152-63.
Panaitof S Carmen, Abrahams Brett S, Dong Hongmei, Geschwind Daniel H, White Stephanie A Language-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds. The Journal of comparative neurology. 2010; 518(11): 1995-2018.