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Joshua Trachtenberg, Ph.D.

Email Address:

Office Address:
NRB 503
Los Angeles, CA 90095

Office Phone Number:
(310) 825-0873

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Department / Division Affiliations
Associate Professor, Neurobiology
Member, ACCESS Program: Dept. of Neurobiology, Access Cell and Developmental Biology Home Area, Access Molecular, Cellular and Integrative Physiology Home Area, Access Neuroscience Home Area, Brain Research Institute, Neuroengineering Training Program, Neuroscience IDP


Joshua Trachtenberg joined the Department of Neurobiology as an Assistant Professor in July of 2003. His research focuses on understanding the cellular and circuit-wide mechanisms that underlie the acquisition and consolidation of memories in the cortex. Prior to joining the UCLA faculty, he was a postdoctoral fellow at the Cold Spring Harbor Laboratory and at the University of California, San Francisco. He received his Ph.D. in developmental neurobiology at the University of Texas at Austin and his Bachelor of Arts degree from Brandeis University.


Li W, Zhou Y, Jentsch JD, Brown RA, Tian X, Ehninger D, Hennah W, Peltonen L, Lonnqvist J, Huttunen MO, Kaprio J, Trachtenberg JT, Silva AJ, Cannon TD. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc Natl Acad Sci U S A 2007; 104(46): 18280-5.
Trachtenberg JT, Chen BE, Knott GW, Feng G, Sanes JR, Welker E, Svoboda K Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature. . 2002; 420(6917): 788-94.
Gdalyahu Amos, Tring Elaine, Polack Pierre-Olivier, Gruver Robin, Golshani Peyman, Fanselow Michael S, Silva Alcino J, Trachtenberg Joshua T Associative fear learning enhances sparse network coding in primary sensory cortex. Neuron. 2012; 75(1): 121-32.
Wyatt Ryan M, Tring Elaine, Trachtenberg Joshua T Pattern and not magnitude of neural activity determines dendritic spine stability in awake mice. Nature neuroscience. 2012; 15(7): 949-51.
Kuhlman Sandra J, Tring Elaine, Trachtenberg Joshua T Fast-spiking interneurons have an initial orientation bias that is lost with vision. Nature neuroscience. 2011; 14(9): 1121-3.
Smith Spencer L, Trachtenberg Joshua T The refinement of ipsilateral eye retinotopic maps is increased by removing the dominant contralateral eye in adult mice. PloS one. 2010; 5(3): e9925.
Matter Cheryl, Pribadi Mochtar, Liu Xin, Trachtenberg Joshua T Delta-catenin is required for the maintenance of neural structure and function in mature cortex in vivo. Neuron. 2009; 64(3): 320-7.
Faguet J, Maranhao B, Smith SL, Trachtenberg JT Ipsilateral eye cortical maps are uniquely sensitive to binocular plasticity. Journal of Neurophysiology 2009; 101(2): 855-61.
Chow DK, Groszer M, Pribadi M, Machniki M, Carmichael ST, Liu X, Trachtenberg JT Laminar and compartmental regulation of dendritic growth in vivo. Nature Neuroscience 2009; 12(2): 116-8.
Smith SL & Trachtenberg JT Experience-dependent binocular competition in the visual cortex begins at eye opening. Nature Neuroscience 2007; 10(3): 370-375.
Holtmaat, AJ Trachtenberg, JT Wilbrecht, L Shepherd, GM Zhang, X Knott, GW Svoboda, K Transient and persistent dendritic spines in the neocortex in vivo. Neuron. . 2005; 45(2): 279-91.
Trachtenberg, JT Stryker, MP Rapid anatomical plasticity of horizontal connections in the developing visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 2001; 21(10): 3476-82.
Trachtenberg, JT Trepel, C Stryker, MP Rapid extragranular plasticity in the absence of thalamocortical plasticity in the developing primary visual cortex. Science. . 2000; 287(5460): 2029-32.
Issa, NP Trachtenberg, JT Chapman, B Zahs, KR Stryker, MP The critical period for ocular dominance plasticity in the Ferret's visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 1999; 19(16): 6965-78.
Trachtenberg, JT Fiber apoptosis in developing rat muscles is regulated by activity, neuregulin. Developmental biology. . 1998; 196(2): 193-203.
Trachtenberg, JT Thompson, WJ Nerve terminal withdrawal from rat neuromuscular junctions induced by neuregulin and Schwann cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 1997; 17(16): 6243-55.
Son, YJ Trachtenberg, JT Thompson, WJ Schwann cells induce and guide sprouting and reinnervation of neuromuscular junctions. Trends in neurosciences. . 1996; 19(7): 280-5.
Trachtenberg, JT Thompson, WJ Schwann cell apoptosis at developing neuromuscular junctions is regulated by glial growth factor. Nature. . 1996; 379(6561): 174-7.