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Yi Sun, Ph.D.

Work Email Address:
ysun@mednet.ucla.edu

Laboratory Address:
Laboratory
635 Charles E. Young Drive South
Los Angeles, CA 90095
UNITED STATES

Office Address:
Office
NRB 351, 635 Charles E. Young Drive South
Los Angeles, CA 90095
UNITED STATES

Lab Number:
(310) 267-2197
310-267-2197
Office Phone Number:
310-825-9506
310-825-9506
Work Phone Number:
310-825-9506



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Department / Division Affiliations
Associate Professor, Psychiatry and Biobehavioral Sciences
Associate Professor In-Residence, Semel Institute for Neuroscience and Human Behavior, Molecular & Medical Pharmacology
Member, ACCESS Program: Dept. of Molecular & Medical Pharmacology, Access Gene Regulation Home Area, Access Molecular Pharmacology: Therapeutics, Diagnostics, and Biology of Disease Home Area, Access Neuroscience Home Area, Access Physics & Biology in Medicine Home Area, Brain Research Institute, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, JCCC Gene Regulation Program Area, Neuroscience IDP, Pharmacology Home Area
Faculty, Molecular Biology IDP, Molecular, Cellular, and Integrative Physiology IDP

Publications:

He, F Ge, W Martinowich, K Becker-Catania, S Coskun, V Zhu, W Wu, H Castro, D Guillemot, F Fan, G de Vellis, J Sun, YE A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nature neuroscience. . 2005; 8(5): 616-25.
Fan, G Martinowich, K Chin, MH He, F Fouse, SD Hutnick, L Hattori, D Ge, W Shen, Y Wu, H ten Hoeve, J Shuai, K Sun, YE DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development (Cambridge, England) . 2005; 132(15): 3345-56.
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Martin, KC Sun, YE To learn better, keep the HAT on. Neuron. . 2004; 42(6): 879-81.
Martinowich, K Hattori, D Wu, H Fouse, S He, F Hu, Y Fan, G Sun, YE DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science. . 2003; 302(5646): 890-3.
Sun, Y Nadal-Vicens, M Misono, S Lin, MZ Zubiaga, A Hua, X Fan, G Greenberg, ME Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell. . 2001; 104(3): 365-76.
Wu Hao, D'Alessio Ana C, Ito Shinsuke, Wang Zhibin, Cui Kairong, Zhao Keji, Sun Yi Eve, Zhang Yi Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes & development. 2011; 25(7): 679-84.
Wilburn Brian, Rudnicki Dobrila D, Zhao Jing, Weitz Tara Murphy, Cheng Yin, Gu Xiaofeng, Greiner Erin, Park Chang Sin, Wang Nan, Sopher Bryce L, La Spada Albert R, Osmand Alex, Margolis Russell L, Sun Yi E, Yang X William An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice. Neuron. 2011; 70(3): 427-40.
Zeng Yan, Tan Miao, Kohyama Jun, Sneddon Marissa, Watson Joseph B, Sun Yi E, Xie Cui-Wei Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011; 31(49): 17800-10.
Wu Hao, D'Alessio Ana C, Ito Shinsuke, Xia Kai, Wang Zhibin, Cui Kairong, Zhao Keji, Sun Yi Eve, Zhang Yi Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature. 2011; 473(7347): 389-93.
Tao Jifang, Wu Hao, Lin Quan, Wei Weizheng, Lu Xiao-Hong, Cantle Jeffrey P, Ao Yan, Olsen Richard W, Yang X William, Mody Istvan, Sofroniew Michael V, Sun Yi E Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011; 31(22): 8306-19.