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Edythe London, Ph.D.

Work Email Address:
elondon@mednet.ucla.edu

Office Address:
Main Office
760 Westwood Plaza
Room C8-532
Los Angeles, CA 90095
UNITED STATES

Work Address:
Office
NPI
Los Angeles, CA 90095
UNITED STATES

Fax Number:
(310) 825-0812
Lab Number:
(310) 825-0606



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Department / Division Affiliations
Director, Center for Addictive Behaviors
Professor, Psychiatry and Biobehavioral Sciences
Professor in Residence, Molecular & Medical Pharmacology
Member, ACCESS Departments, ACCESS Program: Dept. of Molecular & Medical Pharmacology, Access Molecular Pharmacology: Therapeutics, Diagnostics, and Biology of Disease Home Area, Access Neuroscience Home Area, Brain Research Institute, CTSI, Neuroscience IDP, Pharmacology Home Area

Bio:

Dr. London received her Ph.D. in Pharmacology from the University of Maryland (Baltimore) in 1976. Following her post-doctoral fellowship at Johns Hopkins School of Medicine, she worked at the National Institutes of Health (NIH) in the National Institute on Drug Abuse (NIDA) where she was Director of the Brain Imaging Center of the Intramural Research Program. During her tenure at NIDA, Dr. London also held joint faculty appointments at the University of Maryland and Johns Hopkins Schools of Medicine from 1993-1999. In 1999, she joined the faculty at the UCLA Neuropsychiatric Institute and is currently a full professor in the David Geffen School of Medicine at UCLA. She maintains an active NIH-funded research program, and has published over 250 peer-reviewed research articles, as well as numerous book chapters and reviews. Dr. London is an internationally recognized expert in the use of neuroimaging to study neural circuitry underlying drug craving. Dr. London has served on numerous NIH special grant review committees and emphasis panels and she currently is a member of the NIH Clinical Research Review Committee. Complementing her commitment to scientific research and education, Dr. London has mentored graduate students, postdoctoral fellows and junior faculty interested in the multi-faceted problems of substance abuse and drug addiction. Many of her mentees have gone on to prestigious positions in academia and government. Additionally, she is a vocal advocate for junior faculty, providing advice, assistance and training opportunities as young investigators strive to become both productive and independent.

Publications:

Dean Andy C, Groman Stephanie M, Morales Angelica M, London Edythe D An evaluation of the evidence that methamphetamine abuse causes cognitive decline in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2013; 38(2): 259-74.
Jarcho Johanna M, Feier Natasha A, Bert Alberto, Labus Jennifer A, Lee Maunoo, Stains Jean, Ebrat Bahar, Groman Stephanie M, Tillisch Kirsten, Brody Arthur L, London Edythe D, Mandelkern Mark A, Mayer Emeran A Diminished neurokinin-1 receptor availability in patients with two forms of chronic visceral pain. Pain. 2013; 146(2): .
Ghahremani Dara G, Oh Eugene Y, Dean Andrew C, Mouzakis Kristina, Wilson Kristen D, London Edythe D Effects of the Youth Empowerment Seminar on Impulsive Behavior in Adolescents. The Journal of adolescent health : official publication of the Society for Adolescent Medicine. 2013; .
Berman Steven M, London Edythe D, Morgan Melinda, Rapkin Andrea J Elevated gray matter volume of the emotional cerebellum in women with premenstrual dysphoric disorder. Journal of affective disorders. 2013; 146(2): 266-71.
Galván Adriana, Schonberg Tom, Mumford Jeanette, Kohno Milky, Poldrack Russell A, London Edythe D Greater risk sensitivity of dorsolateral prefrontal cortex in young smokers than in nonsmokers. Psychopharmacology. 2013; .
Reise Steven P, Moore Tyler M, Sabb Fred W, Brown Amira K, London Edythe D The Barratt Impulsiveness Scale-11: Reassessment of Its Structure in a Community Sample. Psychological assessment. 2013; 146(2): .
Canamar Catherine P, London Edythe Acute cigarette smoking reduces latencies on a Smoking Stroop test. Addictive behaviors. 2012; 37(5): 627-31.
Hudkins Matthew, O'Neill Joseph, Tobias Marc C, Bartzokis George, London Edythe D Cigarette smoking and white matter microstructure. Psychopharmacology. 2012; 221(2): 285-95.
Groman Stephanie M, Lee Buyean, Seu Emanuele, James Alex S, Feiler Karen, Mandelkern Mark A, London Edythe D, Jentsch J David Dysregulation of D₂-mediated dopamine transmission in monkeys after chronic escalating methamphetamine exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012; 32(17): 5843-52.
Dean Andy C, Hellemann Gerhard, Sugar Catherine A, London Edythe D Educational attainment is not a good proxy for cognitive function in methamphetamine dependence. Drug and alcohol dependence. 2012; 123(1-3): 249-54.
Berman Steven M, Paz-Filho Gilberto, Wong Ma-Li, Kohno Milky, Licinio Julio, London Edythe D Effects of Leptin Deficiency and Replacement on Cerebellar Response to Food-Related Cues. Cerebellum (London, England). 2012; 32(21): .
Morales Angelica M, Lee Buyean, Hellemann Gerhard, O'Neill Joseph, London Edythe D Gray-matter volume in methamphetamine dependence: Cigarette smoking and changes with abstinence from methamphetamine. Drug and alcohol dependence. 2012; 153(4): .
Payer Doris E, Baicy Kate, Lieberman Matthew D, London Edythe D Overlapping neural substrates between intentional and incidental down-regulation of negative emotions. Emotion (Washington, D.C.). 2012; 12(2): 229-35.
Jarcho Johanna M, Mayer Emeran A, Jiang Ziyue Karen, Feier Natasha A, London Edythe D Pain, affective symptoms, and cognitive deficits in patients with cerebral dopamine dysfunction. Pain. 2012; 153(4): 744-54.
Ivanov Iliyan, Liu Xun, Shulz Kurt, Fan Jin, London Edythe, Friston Karl, Halperin Jeffrey M, Newcorn Jeffrey H Parental substance abuse and function of the motivation and behavioral inhibition systems in drug-naïve youth. Psychiatry research. 2012; 201(2): 128-35.
Brown Amira K, Mandelkern Mark A, Farahi Judah, Robertson Chelsea, Ghahremani Dara G, Sumerel Brittany, Moallem Nathasha, London Edythe D Sex differences in striatal dopamine D2/D3 receptor availability in smokers and non-smokers. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2012; 201(2): 1-6.
Ghahremani Dara G, Lee Buyean, Robertson Chelsea L, Tabibnia Golnaz, Morgan Andrew T, De Shetler Natalie, Brown Amira K, Monterosso John R, Aron Adam R, Mandelkern Mark A, Poldrack Russell A, London Edythe D Striatal Dopamine D2/D3 Receptors Mediate Response Inhibition and Related Activity in Frontostriatal Neural Circuitry in Humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012; 32(21): 7316-7324.
Dean Andy C, Sevak Rajkumar J, Monterosso John R, Hellemann Gerhard, Sugar Catherine A, London Edythe D Acute modafinil effects on attention and inhibitory control in methamphetamine-dependent humans. Journal of studies on alcohol and drugs. 2011; 72(6): 943-53.
Tabibnia Golnaz, Monterosso John R, Baicy Kate, Aron Adam R, Poldrack Russell A, Chakrapani Shruthi, Lee Buyean, London Edythe D Different forms of self-control share a neurocognitive substrate. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011; 31(13): 4805-10.
Groman Stephanie M, Lee Buyean, London Edythe D, Mandelkern Mark A, James Alex S, Feiler Karen, Rivera Ronald, Dahlbom Magnus, Sossi Vesna, Vandervoort Eric, Jentsch J David Dorsal striatal D2-like receptor availability covaries with sensitivity to positive reinforcement during discrimination learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011; 31(20): 7291-9.
Culbertson Christopher S, Bramen Jennifer, Cohen Mark S, London Edythe D, Olmstead Richard E, Gan Joanna J, Costello Matthew R, Shulenberger Stephanie, Mandelkern Mark A, Brody Arthur L Effect of bupropion treatment on brain activation induced by cigarette-related cues in smokers. Archives of general psychiatry. 2011; 68(5): 505-15.
Ghahremani Dara G, Tabibnia Golnaz, Monterosso John, Hellemann Gerhard, Poldrack Russell A, London Edythe D Effect of modafinil on learning and task-related brain activity in methamphetamine-dependent and healthy individuals. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2011; 36(5): 950-9.
Brody Arthur L, Mandelkern Mark A, London Edythe D, Khan Aliyah, Kozman Daniel, Costello Matthew R, Vellios Evan E, Archie Meena M, Bascom Rebecca, Mukhin Alexey G Effect of secondhand smoke on occupancy of nicotinic acetylcholine receptors in brain. Archives of general psychiatry. 2011; 68(9): 953-60.
Zorick Todd, Mandelkern Mark A, Lee Buyean, Wong Ma-Li, Miotto Karen, Shabazian Jon, London Edythe D Elevated plasma prolactin in abstinent methamphetamine-dependent subjects. The American journal of drug and alcohol abuse. 2011; 37(1): 62-7.
Dean Andy C, Sugar Catherine A, Hellemann Gerhard, London Edythe D Is all risk bad? Young adult cigarette smokers fail to take adaptive risk in a laboratory decision-making test. Psychopharmacology. 2011; 215(4): 801-11.
Galván Adriana, Poldrack Russell A, Baker Christine M, McGlennen Kristine M, London Edythe D Neural correlates of response inhibition and cigarette smoking in late adolescence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2011; 36(5): 970-8.
Rapkin Andrea J, Berman Steven M, Mandelkern Mark A, Silverman Daniel H S, Morgan Melinda, London Edythe D Neuroimaging evidence of cerebellar involvement in premenstrual dysphoric disorder. Biological psychiatry. 2011; 69(4): 374-80.
Zorick Todd, Sugar Catherine A, Hellemann Gerhard, Shoptaw Steve, London Edythe D Poor response to sertraline in methamphetamine dependence is associated with sustained craving for methamphetamine. Drug and alcohol dependence. 2011; 118(2-3): 500-3.
Nestor Liam J, Ghahremani Dara G, Monterosso John, London Edythe D Prefrontal hypoactivation during cognitive control in early abstinent methamphetamine-dependent subjects. Psychiatry research. 2011; 194(3): 287-95.
London Edythe D, Berman Steven M, Chakrapani Shruthi, Delibasi Tuncay, Monterosso John, Erol H Kutlu, Paz-Filho Gilberto, Wong Ma-Li, Licinio Julio Short-Term Plasticity of Gray Matter Associated with Leptin Deficiency and Replacement. The Journal of clinical endocrinology and metabolism. 2011; 215(4): .
Ernst Monique, Luckenbaugh David A, Moolchan Eric T, Temple Veronica A, Jenness Jessica, Korelitz Katherine E, London Edythe D, Kimes Alane S Decision-making and facial emotion recognition as predictors of substance-use initiation among adolescents. Addictive behaviors. 2010; 35(3): 286-9.
Costello Matthew R, Mandelkern Mark A, Shoptaw Stephen, Shulenberger Stephanie, Baker Stephanie K, Abrams Anna L, Xia Catherine, London Edythe D, Brody Arthur L Effects of treatment for tobacco dependence on resting cerebral glucose metabolism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2010; 35(3): 605-12.
De La Garza Richard, Zorick Todd, London Edythe D, Newton Thomas F Evaluation of modafinil effects on cardiovascular, subjective, and reinforcing effects of methamphetamine in methamphetamine-dependent volunteers. Drug and alcohol dependence. 2010; 106(2-3): 173-80.
Culbertson Christopher, Nicolas Sam, Zaharovits Itay, London Edythe D, De La Garza Richard, Brody Arthur L, Newton Thomas F Methamphetamine craving induced in an online virtual reality environment. Pharmacology, biochemistry, and behavior. 2010; 96(4): 454-60.
Simon Sara L, Dean Andy C, Cordova Xochitl, Monterosso John R, London Edythe D Methamphetamine dependence and neuropsychological functioning: evaluating change during early abstinence. Journal of studies on alcohol and drugs. 2010; 71(3): 335-44.
Payer Doris E, Lieberman Matthew D, London Edythe D Neural Correlates of Affect Processing and Aggression in Methamphetamine Dependence. Archives of general psychiatry. 2010; .
Bauer Michael, Berman Steven M, Schlagenhauf Florian, Voytek Bradley, Rasgon Natalie, Mandelkern Mark A, Whybrow Peter C, London Edythe D Regional cerebral glucose metabolism and anxiety symptoms in bipolar depression: effects of levothyroxine. Psychiatry research. 2010; 181(1): 71-6.
Azizian Allen, Nestor Liam J, Payer Doris, Monterosso John R, Brody Arthur L, London Edythe D Smoking reduces conflict-related anterior cingulate activity in abstinent cigarette smokers performing a Stroop task. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2010; 35(3): 775-82.
Brody Arthur L, London Edythe D, Olmstead Richard E, Allen-Martinez Zoe, Shulenberger Stephanie, Costello Matthew R, Abrams Anna L, Scheibal David, Farahi Judah, Shoptaw Steven, Mandelkern Mark A Smoking-induced change in intrasynaptic dopamine concentration: effect of treatment for Tobacco Dependence. Psychiatry research. 2010; 183(3): 218-24.
Tobias Marc C, O'Neill Joseph, Hudkins Matthew, Bartzokis George, Dean Andrew C, London Edythe D White-matter abnormalities in brain during early abstinence from methamphetamine abuse. Psychopharmacology. 2010; 209(1): 13-24.
Zorick Todd, Nestor Liam, Miotto Karen, Sugar Catherine, Hellemann Gerhard, Scanlon Graham, Rawson Richard, London Edythe D Withdrawal symptoms in abstinent methamphetamine-dependent subjects. Addiction (Abingdon, England). 2010; 105(10): 1809-18.
Brody Arthur L, Mandelkern Mark A, Costello Matthew R, Abrams Anna L, Scheibal David, Farahi Judah, London Edythe D, Olmstead Richard E, Rose Jed E, Mukhin Alexey G Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2009; 12(3): 305-16.
Rao Uma, Hammen Constance L, London Edythe D, Poland Russell E Contribution of hypothalamic-pituitary-adrenal activity and environmental stress to vulnerability for smoking in adolescents. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2009; 34(13): 2721-32.
Brody Arthur L, Olmstead Richard E, Abrams Anna L, Costello Matthew R, Khan Aliyah, Kozman Daniel, Saxena Sanjaya, Farahi Judah, London Edythe D, Mandelkern Mark A Effect of a history of major depressive disorder on smoking-induced dopamine release. Biological psychiatry. 2009; 66(9): 898-901.
London Edythe D, Berman Steven M, Mohammadian Parvenah, Ritchie Terrie, Mandelkern Mark A, Susselman Mary K W, Schlagenhauf Florian, Noble Ernest P Effect of the TaqIA polymorphism on ethanol response in the brain. Psychiatry research. 2009; 174(3): 163-70.
Henningfield Jack E, London Edythe D, Pogun Sakire Handbook of experimental pharmacology 192. Nicotine psychopharmacology. Preface. Handbook of experimental pharmacology. 2009; 100(192): v-viii.
Berman Steven M, Noble Ernest P, Mohammadian Parvaneh, Ritchie Terry, Mandelkern Mark A, London Edythe D Laterality of cortical response to ethanol is moderated by TaqIA A1 allele. Synapse (New York, N.Y.). 2009; 63(9): 817-21.
Azizian Allen, Monterosso John, O'Neill Joseph, London Edythe D Magnetic resonance imaging studies of cigarette smoking. Handbook of experimental pharmacology. 2009; 100(192): 113-43.
Zorick Todd, Sevak Rajkumar J, Miotto Karen, Shoptaw Steven, Swanson Aimee-Noelle, Clement Clayton, De La Garza Richard, Newton Thomas F, London Edythe D Pilot Safety Evaluation of Varenicline for the Treatment of Methamphetamine Dependence. Journal of experimental pharmacology. 2009; 2010(2): 13-18.
SM Berman, RT Kuczenski, JT McCracken, ED London Potential adverse effects of amphetamine treatment on brain and behavior: a review. Mol. Psychiatry 2009; 14(2): 123-142.
Dean Andy C, London Edythe D, Sugar Catherine A, Kitchen Christina M R, Swanson Aimee-Noelle, Heinzerling Keith G, Kalechstein Ari D, Shoptaw Steven Predicting adherence to treatment for methamphetamine dependence from neuropsychological and drug use variables. Drug and alcohol dependence. 2009; 105(1-2): 48-55.
Lee Buyean, London Edythe D, Poldrack Russell A, Farahi Judah, Nacca Angelo, Monterosso John R, Mumford Jeanette A, Bokarius Andrew V, Dahlbom Magnus, Mukherjee Jogeshwar, Bilder Robert M, Brody Arthur L, Mandelkern Mark A Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009; 29(47): 14734-40.
London Edythe D Studying addiction in the age of neuroimaging. Marian W. Fischman Lecture given at the 2008 meeting of CPDD. Drug and alcohol dependence. 2009; 100(1-2): 182-5.
Prosser James, London Edythe D, Galynker Igor I Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: performance and neuroimaging results. Drug and alcohol dependence. 2009; 104(3): 228-40.
De La Garza Richard, Zorick Todd, Heinzerling Keith G, Nusinowitz Steve, London Edythe D, Shoptaw Steven, Moody David E, Newton Thomas F The cardiovascular and subjective effects of methamphetamine combined with gamma-vinyl-gamma-aminobutyric acid (GVG) in non-treatment seeking methamphetamine-dependent volunteers. Pharmacology, biochemistry, and behavior. 2009; 94(1): 186-93.
Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Allen-Martinez Zoe, Scheibal David, Abrams Anna L, Costello Matthew R, Farahi Judah, Saxena Sanjaya, Monterosso John, London Edythe D Ventral striatal dopamine release in response to smoking a regular vs a denicotinized cigarette. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2009; 34(2): 282-9.
Berman Steven, O'Neill Joseph, Fears Scott, Bartzokis George, London Edythe D Abuse of amphetamines and structural abnormalities in the brain. Annals of the New York Academy of Sciences. 2008; 1141(2): 195-220.
Prosser James M, Eisenberg Daniel, Davey Emily E, Steinfeld Matthew, Cohen Lisa J, London Edythe D, Galynker Igor I Character pathology and neuropsychological test performance in remitted opiate dependence. Substance abuse treatment, prevention, and policy. 2008; 3(2): 23.
Payer Doris E, Lieberman Matthew D, Monterosso John R, Xu Jiansong, Fong Timothy W, London Edythe D Differences in cortical activity between methamphetamine-dependent and healthy individuals performing a facial affect matching task. Drug and alcohol dependence. 2008; 93(1-2): 93-102.
Chefer Svetlana I, Kimes Alane S, Matochik John A, Horti Andrew G, Kurian Varughese, Shumway Dean, Domino Edward F, London Edythe D, Mukhin Alexey G Estimation of D2-like receptor occupancy by dopamine in the putamen of hemiparkinsonian Monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2008; 33(2): 270-8.
Xu Jiansong, Azizian Allen, Monterosso John, Domier Catherine P, Brody Arthur L, Fong Timothy W, London Edythe D Gender effects on mood and cigarette craving during early abstinence and resumption of smoking. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2008; 10(11): 1653-61.
Ivanov Iliyan, Schulz Kurt P, London Edythe D, Newcorn Jeffrey H Inhibitory control deficits in childhood and risk for substance use disorders: a review. The American journal of drug and alcohol abuse. 2008; 34(3): 239-58.
Azizian Allen, Monterosso John R, Brody Arthur L, Simon Sara L, London Edythe D Severity of nicotine dependence moderates performance on perceptual-motor tests of attention. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2008; 10(4): 599-606.
Galynker Igor I, Eisenberg Daniel, Matochik John A, Gertmenian-King Enid, Cohen Lisa, Kimes Alane S, Contoreggi Carlo, Kurian Varughese, Ernst Monique, Rosenthal Richard N, Prosser James, London Edythe D Cerebral metabolism and mood in remitted opiate dependence. Drug and alcohol dependence. 2007; 90(2-3): 166-74.
Baicy Kate, London Edythe D Corticolimbic dysregulation and chronic methamphetamine abuse. Addiction (Abingdon, England). 2007; 102 Suppl 1(5): 5-15.
Lee Buyean, Groman Stephanie, London Edythe D, Jentsch James David Dopamine D2/D3 receptors play a specific role in the reversal of a learned visual discrimination in monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2007; 32(10): 2125-34.
Xu Jiansong, Mendrek Adrianna, Cohen Mark S, Monterosso John, Simon Sara, Jarvik Murray, Olmstead Richard, Brody Arthur L, Ernst Monique, London Edythe D Effect of cigarette smoking on prefrontal cortical function in nondeprived smokers performing the Stroop Task. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2007; 32(6): 1421-8.
Domier Catherine P, Monterosso John R, Brody Arthur L, Simon Sara L, Mendrek Adrianna, Olmstead Richard, Jarvik Murray E, Cohen Mark S, London Edythe D Effects of cigarette smoking and abstinence on Stroop task performance. Psychopharmacology. 2007; 195(1): 1-9.
Monterosso John R, Ainslie George, Xu Jiansong, Cordova Xochitl, Domier Catherine P, London Edythe D Frontoparietal cortical activity of methamphetamine-dependent and comparison subjects performing a delay discounting task. Human brain mapping. 2007; 28(5): 383-93.
Maki Pauline M, Ernst Monique, London Edythe D, Mordecai Kristen L, Perschler Pamela, Durso Samuel C, Brandt Jason, Dobs Adrian, Resnick Susan M Intramuscular testosterone treatment in elderly men: evidence of memory decline and altered brain function. The Journal of clinical endocrinology and metabolism. 2007; 92(11): 4107-14.
Baicy Kate, London Edythe D, Monterosso John, Wong Ma-Li, Delibasi Tuncay, Sharma Anil, Licinio Julio Leptin replacement alters brain response to food cues in genetically leptin-deficient adults. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(46): 18276-9.
Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Jou Jennifer, Tiongson Emmanuelle, Allen Valerie, Scheibal David, London Edythe D, Monterosso John R, Tiffany Stephen T, Korb Alex, Gan Joanna J, Cohen Mark S Neural substrates of resisting craving during cigarette cue exposure. Biological psychiatry. 2007; 62(6): 642-51.
Ernst Monique, Luckenbaugh David A, Moolchan Eric T, Leff Michelle K, Allen Rachel, Eshel Neir, London Edythe D, Kimes Alane Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder. Pediatrics. 2006; 117(6): 2030-9.
Brody Arthur L, Mandelkern Mark A, London Edythe D, Olmstead Richard E, Farahi Judah, Scheibal David, Jou Jennifer, Allen Valerie, Tiongson Emmanuelle, Chefer Svetlana I, Koren Andrei O, Mukhin Alexey G Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors. Archives of general psychiatry. 2006; 63(8): 907-15.
Xu Jiansong, Mendrek Adrianna, Cohen Mark S, Monterosso John, Simon Sara, Brody Arthur L, Jarvik Murray, Rodriguez Paul, Ernst Monique, London Edythe D Effects of acute smoking on brain activity vary with abstinence in smokers performing the N-Back task: a preliminary study. Psychiatry research. 2006; 148(2-3): 103-9.
Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Scheibal David, Hahn Emily, Shiraga Sharon, Zamora-Paja Eleanor, Farahi Judah, Saxena Sanjaya, London Edythe D, McCracken James T Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens. Archives of general psychiatry. 2006; 63(7): 808-16.
Staley Julie K, Krishnan-Sarin Suchitra, Cosgrove Kelly P, Krantzler Erica, Frohlich Erin, Perry Edward, Dubin Joel A, Estok Kristina, Brenner Eric, Baldwin Ronald M, Tamagnan Gilles D, Seibyl John P, Jatlow Peter, Picciotto Marina R, London Edythe D, O'Malley Stephanie, van Dyck Christopher H Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006; 26(34): 8707-14.
Wong Dean F, Kuwabara Hiroto, Schretlen David J, Bonson Katherine R, Zhou Yun, Nandi Ayon, Brasi? James R, Kimes Alane S, Maris Marika A, Kumar Anil, Contoreggi Carlo, Links Jonathan, Ernst Monique, Rousset Olivier, Zukin Stephen, Grace Anthony A, Lee Jae Sung, Rohde Charles, Jasinski Donald R, Gjedde Albert, London Edythe D Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2006; 31(12): 2716-27.
Prosser James, Cohen Lisa J, Steinfeld Matthew, Eisenberg Daniel, London Edythe D, Galynker Igor I Neuropsychological functioning in opiate-dependent subjects receiving and following methadone maintenance treatment. Drug and alcohol dependence. 2006; 84(3): 240-7.
Mendrek Adrianna, Monterosso John, Simon Sara L, Jarvik Murray, Brody Arthur, Olmstead Richard, Domier Catherine P, Cohen Mark S, Ernst Monique, London Edythe D Working memory in cigarette smokers: comparison to non-smokers and effects of abstinence. Addictive behaviors. 2006; 31(5): 833-44.
Xu Jiansong, Mendrek Adrianna, Cohen Mark S, Monterosso John, Rodriguez Paul, Simon Sara L, Brody Arthur, Jarvik Murray, Domier Catherine P, Olmstead Richard, Ernst Monique, London Edythe D Brain activity in cigarette smokers performing a working memory task: effect of smoking abstinence. Biological psychiatry. 2005; 58(2): 143-50.
London Edythe D, Berman Steven M, Voytek Bradley, Simon Sara L, Mandelkern Mark A, Monterosso John, Thompson Paul M, Brody Arthur L, Geaga Jennifer A, Hong Michael S, Hayashi Kiralee M, Rawson Richard A, Ling Walter Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers. Biological psychiatry. 2005; 58(10): 770-8.
Fishbein Diana, Hyde Chris, Eldreth Diana, London Edythe D, Matochik John, Ernst Monique, Isenberg Nancy, Steckley Stacey, Schech Barry, Kimes Alane Cognitive performance and autonomic reactivity in abstinent drug abusers and nonusers. Experimental and clinical psychopharmacology. 2005; 13(1): 25-40.
Baicy Kate, Bearden Carrie E, Monterosso John, Brody Arthur L, Isaacson Andrew J, London Edythe D Common substrates of dysphoria in stimulant drug abuse and primary depression: therapeutic targets. International review of neurobiology. 2005; 65(2): 117-45.
Monterosso John R, Aron Adam R, Cordova Xochitl, Xu Jiansong, London Edythe D Deficits in response inhibition associated with chronic methamphetamine abuse. Drug and alcohol dependence. 2005; 79(2): 273-7.
Voytek Bradley, Berman Steven M, Hassid B Daniel, Simon Sara L, Mandelkern Mark A, Brody Arthur L, Monterosso John, Ling Walter, London Edythe D Differences in regional brain metabolism associated with marijuana abuse in methamphetamine abusers. Synapse (New York, N.Y.). 2005; 57(2): 113-5.
Eisenberg Daniel P, London Edythe D, Matochik John A, Derbyshire Stuart, Cohen Lisa J, Steinfeld Matthew, Prosser James, Galynker Igor I Education-associated cortical glucose metabolism during sustained attention. Neuroreport. 2005; 16(13): 1473-6.
Matochik John A, London Edythe D, Yildiz Bulent O, Ozata Metin, Caglayan Sinan, DePaoli Alex M, Wong Ma-Li, Licinio Julio Effect of leptin replacement on brain structure in genetically leptin-deficient adults. The Journal of clinical endocrinology and metabolism. 2005; 90(5): 2851-4.
Gündisch Daniela, Koren Andrei O, Horti Andrew G, Pavlova Olga A, Kimes Alane S, Mukhin Alexey G, London Edythe D In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors. Synapse (New York, N.Y.). 2005; 55(2): 89-97.
Vaupel D Bruce, Tella Srihari R, Huso David L, Wagner Valentine O, Mukhin Alexey G, Chefer Svetlana I, Horti Andrew G, London Edythe D, Koren Andrei O, Kimes Alane S Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography. The Journal of pharmacology and experimental therapeutics. 2005; 312(1): 355-65.
Fishbein Diana H, Eldreth Diana L, Hyde Christopher, Matochik John A, London Edythe D, Contoreggi Carlo, Kurian Varughese, Kimes Alane S, Breeden Andrew, Grant Steven Risky decision making and the anterior cingulate cortex in abstinent drug abusers and nonusers. Brain research. Cognitive brain research. 2005; 23(1): 119-36.
Obrzut Sebastian L, Koren Andrei O, Mandelkern Mark A, Brody Arthur L, Hoh Carl K, London Edythe D Whole-body radiation dosimetry of 2-[18F]Fluoro-A-85380 in human PET imaging studies. Nuclear medicine and biology. 2005; 32(8): 869-74.
Matochik John A, Chefer Svetlana I, Lane Mark A, Roth George S, Mattison Julie A, London Edythe D, Ingram Donald K Age-related decline in striatal volume in rhesus monkeys: assessment of long-term calorie restriction. Neurobiology of aging. 2004; 25(2): 193-200.
Brody Arthur L, Mandelkern Mark A, Lee Grace, Smith Erlyn, Sadeghi Mary, Saxena Sanjaya, Jarvik Murray E, London Edythe D Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study. Psychiatry research. 2004; 130(3): 269-81.
Brody Arthur L, Mandelkern Mark A, Jarvik Murray E, Lee Grace S, Smith Erlyn C, Huang Joe C, Bota Robert G, Bartzokis George, London Edythe D Differences between smokers and nonsmokers in regional gray matter volumes and densities. Biological psychiatry. 2004; 55(1): 77-84.
Rotheram-Fuller Erin, Shoptaw Steven, Berman Steven M, London Edythe D Impaired performance in a test of decision-making by opiate-dependent tobacco smokers. Drug and alcohol dependence. 2004; 73(1): 79-86.
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