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Alan Grinnell, Ph.D.

Email Address:
adg@ucla.edu

Work Address:
Laboratory
CHS
Los Angeles, CA 90095
UNITED STATES

Office
Dept. of Physiology,
David Geffen School of Medicine at UCLA
Los Angeles, CA 90095
UNITED STATES

Work Phone Number:
(310) 825-7870
310-825-4468



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Department / Division Affiliations
Professor, Physiology
Member, ACCESS Program: Dept. of Molecular, Cell & Integrative Physiology, Brain Research Institute
Faculty, Molecular, Cellular, and Integrative Physiology IDP

Bio:

Dr. Grinnell received his B.A. in 1958 and his PhD in 1962, both from Harvard. He did postdoctoral training in the laboratory of Prof. Bernard Katz, University College London (1962-64) and with Prof. T. H. Bullock, UCLA, (1964-65). He was appointed an Assitant Prof. of Biology at UCLA in 1964, Assoc. Prof. in 1966, and Full Prof. in 1971. Since 1972 he has been a Prof. in the Dept. of Physiology. In 1977 he was named Head of the Ahmanson Laboratory of Neurobiology in the BRI, and from 1978-2002 was Director of the Jerry Lewis Neuromuscular Research Center. IN 1997 he joined the Dept. of Physiological Science and chaired that department until 2001. Since 1990, he has been a Researtch Associate of the Fowler Museum of Cultural History.

Publications:

Grinnell, A.D. Echolocation I: Behavior. New Encyclopedia of Neuroscience, ed. L. R. Squire, in press, 2007; .
Grinnell, A.D. How Muscle Stretch In fluences Neuromuscular Transmission, ed. L. R. Squire, in press. New Encyclopedia of Neuroscience 2007; .
Sun, X-P, Yazejian, B. and Grinnell, A.D. Electrophysiological properties of BK channels in Xenopus motor nerve terminals. J. Physiol. 2004; 557: 207-228.
Grinnell, A.D., Chen, B.-M., Kashani, A., Lin, J., Suzuki, K., and Kidokoro, Y. The role of integrins in the modulation of neurotransmitter release from motor nerve terminals by stretch and hypertonicity.. J. Neurocytol. 2003; 32: 489-503.
Kashani, A., Chen, B.-M., and Grinnell Osmotic modulation of transmitter release from frog motor nerve terminals: Ca++-independence and role of integrins.. J. Physiol. 2001; 530: 243-252.
Yazejian, B, Sun, X.-P, and Grinnell, A.D. Tracking presynaptic Ca++ dynamics during neurotransmitter release with Ca-activated K+ channels.. Nature Neuroscience 2000; 3: 566-571.
Kalko, E.K.V., Schnitzler, H.-U., Kaipf, I & Grinnell, A.D. Hunting and echolocation behavior in Noctilio albiventris: the evolution of piscivory.. Behavioral Ecology and Sociobiology 1998; 45: 305-319.
Chen, B.M and Grinnell, A.D. Kinetics, Ca++ dependence, and biophysical properties of integrin-mediated mechanical modulation of transmitter release from frog motor nerve terminals.. J. Neuroscience 1997; 17: 904-916.
Chen, B.M. and Grinnell, A.D. Integrins help mediate the stretch-induced modulation of transmitter release from frog motor nerve terminals.. Science 1995; 269: 1578-1580.
Sun, XP Yazejian, B Grinnell, AD Electrophysiological properties of BK channels in Xenopus motor nerve terminals.. The Journal of physiology. . 2004; 557(Pt 1): 207-28.
Suzuki, K Grinnell, AD Kidokoro, Y Hypertonicity-induced transmitter release at Drosophila neuromuscular junctions is partly mediated by integrins and cAMP/protein kinase A.. The Journal of physiology. . 2002; 538(Pt 1): 103-19.
Sand, O Chen, BM Grinnell, AD Contribution of L-type Ca(2+) channels to evoked transmitter release in cultured Xenopus nerve-muscle synapses.. The Journal of physiology. . 2001; 536(Pt 1): 21-33.
Yazejian, B DiGregorio, DA Vergara, JL Poage, RE Meriney, SD Grinnell, AD Direct measurements of presynaptic calcium and calcium-activated potassium currents regulating neurotransmitter release at cultured Xenopus nerve-muscle synapses.. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 1997; 17(9): 2990-3001.
Harada, Y Grinnell, AD Regeneration of specific innervation in Xenopus pectoralis muscle.. Journal of neurobiology. . 1996; 31(4): 433-48.
Grinnell, AD Harada, Y Specificity and development of innervation pattern of Xenopus pectoralis muscle.. Journal of neurobiology. . 1996; 31(4): 415-32.
Grinnell, AD Dynamics of nerve-muscle interaction in developing and mature neuromuscular junctions.. Physiological reviews. . 1995; 75(4): 789-834.