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Alvaro Sagasti, Ph.D.

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Sagasti lab
P.O. Box 951606
Los Angeles, CA 90095

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P.O. Box 951606


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Department / Division Affiliations
Associate Professor, Molecular, Cell, and Developmental Biology
Member, ACCESS Program: Dept. of Molecular, Cell & Developmental Biology, Access Cell and Developmental Biology Home Area, Access Neuroscience Home Area, Brain Research Institute, Neuroscience IDP


Dr. Sagasti received his PhD from UCSF, where he worked with Cori Bargmann studying celll specification and left/right asymmetry in the nervous system of the nematode C. elegans. He began his work with zebrafish at the Skirball Institute, NYU Medical Center as a post-doc with Alex Schier. In the summer of 2005 he was a Grass Foundation Fellow at the Marine Biological Labs in Woods Hole, Massachussetts. His work focuses on the development and regeneration of sensory axon arbors in the peripheral nervous system, combining imaging, genetic, and behavioral approaches. He began as a UCLA faculty member in the MCDB department in September 2005.


Rieger Sandra, Wang Fang, Sagasti Alvaro Time-lapse imaging of neural development: Zebrafish lead the way into the fourth dimension. Genesis (New York, N.Y. : 2000). 2011; 214(Pt 6): .
Martin Seanna M, O'Brien Georgeann S, Portera-Cailliau Carlos, Sagasti Alvaro Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning. Development (Cambridge, England). 2010; 137(23): 3985-94.
Grueber Wesley B, Sagasti Alvaro Self-avoidance and tiling: Mechanisms of dendrite and axon spacing. Cold Spring Harbor perspectives in biology. 2010; 2(9): a001750.
O'Brien Georgeann S, Martin Seanna M, Söllner Christian, Wright Gavin J, Becker Catherina G, Portera-Cailliau Carlos, Sagasti Alvaro Developmentally regulated impediments to skin reinnervation by injured peripheral sensory axon terminals. Current biology : CB. 2009; 19(24): 2086-90.
O'Brien Georgeann S, Rieger Sandra, Martin Seanna M, Cavanaugh Ann M, Portera-Cailliau Carlos, Sagasti Alvaro Two-photon axotomy and time-lapse confocal imaging in live zebrafish embryos. Journal of visualized experiments : JoVE. 2009; 2(24): pe30.
Richler Esther, Chaumont Severine, Shigetomi Eiji, Sagasti Alvaro, Khakh Baljit S Tracking transmitter-gated P2X cation channel activation in vitro and in vivo. Nature methods. 2008; 5(1): 87-93.
Sagasti, A Guido, MR Raible, DW Schier, AF. Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current biology . 2005; 15(9): 804-14.