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Allan Wu, M.D.

Work Email Address:
allanwu@mednet.ucla.edu

Mailing Address:
UCLA Neuro
BOX 951769, A-135 RNRC
Los Angeles, CA 90095
UNITED STATES

710 Westwood Plaza

UNITED STATES

Fax Number:
310-206-9819
Work Phone Number:
(310) 794-1195
310-206-6496



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Department / Division Affiliations
Assistant Professor, Neurology
Member, Brain Research Institute, CTSI

Research Interest:

Investigation of the brain-behavior relationships that are responsible for the clinical expression of symptoms and signs

Dr. Wu?s primary research interest is the investigation of the brain-behavior relationships that are responsible for the clinical expression of symptoms and signs in patients affected by neurologic disorders, in particular, those patients affected by movement disorders such as Parkinson?s disease (PD). We are particularly interested in functional changes that occur in the cerebral cortex in response to subcortical dysfunction that can be probed with noninvasive techniques such as transcranial magnetic stimulation (TMS). Current projects include a study of repetitive TMS effects on mood and motor function in atypical parkinsonism; a study of the role of the motor cortex in planning discrete and continuous movements in Parkinson?s disease; studies using both fMRI and TMS to map circuits related to motor learning in stroke and Parkinson?s disease patients.

Publications:

Peters Megan A K, Thompson Benjamin, Merabet Lotfi B, Wu Allan D, Shams Ladan Anodal tDCS to V1 blocks visual perceptual learning consolidation. Neuropsychologia. 2013; 51(7): 1234-1239.
Lin Chien-Ho Janice, Chiang Ming-Chang, Wu Allan D, Iacoboni Marco, Udompholkul Parima, Yazdanshenas Omid, Knowlton Barbara J Age related differences in the neural substrates of motor sequence learning after interleaved and repetitive practices. NeuroImage. 2012; 10(1): .
Meister Ingo G, Wu Allan D, Deblieck Choi, Iacoboni Marco Early semantic and phonological effects on temporal- and muscle-specific motor resonance. The European journal of neuroscience. 2012; .
Lin Chien-Ho Janice, Chiang Ming-Chang, Wu Allan D, Iacoboni Marco, Udompholkul Parima, Yazdanshenas Omid, Knowlton Barbara J Enhanced motor learning in older adults is accompanied by increased bilateral frontal and fronto-parietal connectivity. Brain connectivity. 2012; 2(2): 56-68.
Lin Chien-Ho Janice, Chiang Ming-Chang, Knowlton Barbara J, Iacoboni Marco, Udompholkul Parima, Wu Allan D Interleaved practice enhances skill learning and the functional connectivity of fronto-parietal networks. Human brain mapping. 2012; 222(1): .
Lin Chien-Ho Janice, Knowlton Barbara J, Chiang Ming-Chang, Iacoboni Marco, Udompholkul Parima, Wu Allan D Brain-behavior correlates of optimizing learning through interleaved practice. NeuroImage. 2011; 56(3): 1758-72.
Qi Feng, Wu Allan D, Schweighofer Nicolas Fast estimation of transcranial magnetic stimulation motor threshold. Brain stimulation. 2011; 4(1): 50-7.
Lin Chien-Ho Janice, Wu Allan D, Udompholkul Parima, Knowlton Barbara J Contextual interference effects in sequence learning for young and older adults. Psychology and aging. 2010; 25(4): 929-39.
Lin Chien-Ho Janice, Winstein Carolee J, Fisher Beth E, Wu Allan D Neural correlates of the contextual interference effect in motor learning: a transcranial magnetic stimulation investigation. Journal of motor behavior. 2010; 42(4): 223-32.
Fisher Beth E, Davenport Todd E, Kulig Kornelia, Wu Allan D Identification of potential neuromotor mechanisms of manual therapy in patients with musculoskeletal disablement: rationale and description of a clinical trial. BMC neurology. 2009; 9(7): 20.
Lin Chien-Ho Janice, Fisher Beth E, Wu Allan D, Ko Yi-An, Lee Lung-Yee, Winstein Carolee J Neural correlate of the contextual interference effect in motor learning: a kinematic analysis. Journal of motor behavior. 2009; 41(3): 232-42.
Song Jooeun, Fisher Beth E, Petzinger Giselle, Wu Allan, Gordon James, Salem George J The relationships between the unified Parkinson's disease rating scale and lower extremity functional performance in persons with early-stage Parkinson's disease. Neurorehabilitation and neural repair. 2009; 23(7): 657-61.
Bystritsky Alexander, Kaplan Jonas T, Feusner Jamie D, Kerwin Lauren E, Wadekar Mitali, Burock Mark, Wu Allan D, Iacoboni Marco A preliminary study of fMRI-guided rTMS in the treatment of generalized anxiety disorder. The Journal of clinical psychiatry. 2008; 69(7): 1092-8.
Lin Chien-Ho Janice, Fisher Beth E, Winstein Carolee J, Wu Allan D, Gordon James Contextual interference effect: elaborative processing or forgetting-reconstruction? A post hoc analysis of transcranial magnetic stimulation-induced effects on motor learning. Journal of motor behavior. 2008; 40(6): 578-86.
Deblieck Choi, Thompson Benjamin, Iacoboni Marco, Wu Allan D Correlation between motor and phosphene thresholds: a transcranial magnetic stimulation study. Human brain mapping. 2008; 29(6): 662-70.
Deblieck Choi, Wu Allan D Neuroimaging of nonmotor features of Parkinson's disease. Reviews in neurological diseases. 2008; 5(3): 125-33.
Wu Allan D, Fregni Felipe, Simon David K, Deblieck Choi, Pascual-Leone Alvaro Noninvasive brain stimulation for Parkinson's disease and dystonia. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2008; 5(2): 345-61.
Fisher Beth E, Wu Allan D, Salem George J, Song Jooeun, Lin Chien-Ho Janice, Yip Jeanine, Cen Steven, Gordon James, Jakowec Michael, Petzinger Giselle The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease. Archives of physical medicine and rehabilitation. 2008; 89(7): 1221-9.
Wu Allan D, Petzinger Giselle M, Lin Chien-Ho J, Kung Myron, Fisher Beth Asymmetric corticomotor excitability correlations in early Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. 2007; 22(11): 1587-93.
Molnar-Szakacs Istvan, Wu Allan D, Robles Francisco J, Iacoboni Marco Do you see what I mean? Corticospinal excitability during observation of culture-specific gestures. PloS one. 2007; 2(7): e626.
Lin Chien-Ho Janice, Sullivan Katherine J, Wu Allan D, Kantak Shailesh, Winstein Carolee J Effect of task practice order on motor skill learning in adults with Parkinson disease: a pilot study. Physical therapy. 2007; 87(9): 1120-31.
Wu Allan D Functional neuroimaging and repetitive transcranial magnetic stimulation in Parkinson's disease. Reviews in neurological diseases. 2007; 4(1): 1-9.
Koski Lisa, Lin Janice Chien-Ho, Wu Allan D, Winstein Carolee J Reliability of intracortical and corticomotor excitability estimates obtained from the upper extremities in chronic stroke. Neuroscience research. 2007; 58(1): 19-31.
Meister Ingo G, Wilson Stephen M, Deblieck Choi, Wu Allan D, Iacoboni Marco The essential role of premotor cortex in speech perception. Current biology : CB. 2007; 17(19): 1692-6.
Dong Yun, Dobkin Bruce H, Cen Steven Y, Wu Allan D, Winstein Carolee J Motor cortex activation during treatment may predict therapeutic gains in paretic hand function after stroke. Stroke; a journal of cerebral circulation. 2006; 37(6): 1552-5.
Koski Lisa, Schrader Lara M, Wu Allan D, Stern John M Normative data on changes in transcranial magnetic stimulation measures over a ten hour period. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2005; 116(9): 2099-109.